Defining Pre-Osteoarthritis Is Key to Prevention

Defining Pre-Osteoarthritis Is Key to Prevention

Dear Editor: The article on “Pre-Osteoarthritis: Definition and Diagnosis of an Elusive Clinical Entity” by Ryd et al. is of great interest and importance. The concept and definition of “pre-osteoarthritis” has been a focus of my research program for more than a decade. Some of our prior work was summarized in an open access article from 2012 titled “Early Diagnosis to Enable Early Treatment of...

Understanding Pre-Type 1 Diabetes: The Key to Prevention

While the incidence of type 1 diabetes continues to rise by 3% each year, the ability to prevent this disease remains elusive. Hybrid closed loop devices, artificial pancreas systems, and continuous glucose monitoring technology have helped to ease the daily burden for many people living with type 1 diabetes. However, the artificial pancreas is not a cure; more research is needed to achieve our...

Pre-Osteoarthritis

OBJECTIVE An attempt to define pre-osteoarthritis (OA) versus early OA and definitive osteoarthritis. METHODS A group of specialists in the field of cartilage science and treatment was formed to consider the nature of OA onset and its possible diagnosis. RESULTS Late-stage OA, necessitating total joint replacement, is the end stage of a biological process, with many previous earlier stages....

Improving pre-pregnancy health is key to reducing infant mortality.

Defining osteoarthritis: a moving target.

1063-4584/$ – see front matter 2011 Osteoarthritis doi:10.1016/j.joca.2011.10.008 The challenge of disease definition in osteoarthritis (OA) continues to grow. As described by Pereira et al., in a recent issue of Osteoarthritis and Cartilage (OAC), there are substantial differences in prevalence and incidence estimates when defining OA by radiographic changes alone, as symptomatic OA (requiring...